Long-Term Dietary Supplementation of Pomegranates, Figs and Dates Alleviate Neuroinflammation in a Transgenic Mouse Model of Alzheimer’s Disease
Fig 2
Effects of pomegranates, figs, or dates on the Aβ and ATP levels in the cortex and hippocampus.
The levels of Aβ1–40 and Aβ1–42 in the cortex [A] and hippocampus [B] in WT and TG mice, fed a control diet or a diet supplemented with 4% total extracts of pomegranates [PGs], figs, or dates, as indicated, were determined by the ELISA as described in the Materials and Methods. [C] The % ATP levels in the cortex (Blue bars) and hippocampus (red bars) in WT or TG mice fed a control diet or a diet supplemented with pomegranates, figs, or dates are presented. The representative data from at least three independent experiments are shown (** p<0.01 and *** p<0.001 vs. control TG group; n = 16/group).