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Diet-Induced Obesity in Male C57BL/6 Mice Decreases Fertility as a Consequence of Disrupted Blood-Testis Barrier

Fig 1

Description of an obese mouse model established after 10 weeks on HFD.

(A) Representative picture of 15-week old obese and control mice. (B) Comparison of time-dependent increases in body weight between CD (n = 27) and HFD groups (n = 30). (C) Weekly food consumption by mice in CD and HFD groups. (D) Hematoxylin and eosin-stained hepatic sections from mice both fed control diet (CD) and high-fat diet (HFD). (D2) and (D4) are two-fold enlarged views of (D1) and (D3). Scale bars = 50 μm. Data are expressed as mean ± SEM. * P<0.05, ** P<0.01.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0120775.g001