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The Interaction between Circulating Complement Proteins and Cutaneous Microvascular Endothelial Cells in the Development of Childhood Henoch-Schönlein Purpura

Fig 6

The production of C3 and C5 by HMVEC-d.

HMVEC-d were pre-incubated with plasma of patients with acute HSP (N = 30) or plasma of healthy controls (N = 30) for 48 hr, and then the cells were washed and re-cultured in serum free medium for another 48 hr. C3 (A) and C5 (B) levels in culture supernatants were analyzed by ELISA. * denotes p < 0.01.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0120411.g006