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Change in the Cortical Complexity of Spinocerebellar Ataxia Type 3 Appears Earlier than Clinical Symptoms

Fig 7

The progression rates of cortical atrophy in the supratentorial regions were similar.

(a) Excluding the age effect, the 3D-FD values of 32 cerebral regions had significant negative correlations with disease duration. (b) No significant difference was observed among these individual regions using ANOVA with Bonferroni post-hoc analysis (Degrees of freedom for regions = 98 and F = 0.02).

Fig 7

doi: https://doi.org/10.1371/journal.pone.0118828.g007