The Role of Cellular Coupling in the Spontaneous Generation of Electrical Activity in Uterine Tissue
Fig 9
Occurrence of spiral waves of activity in a 50 × 50 lattice of coupled myocytes and passive cells, observed for inter-myocyte coupling strength, Gm = 12nS. (a) Snapshots of membrane potential are shown at intervals of T = 100ms, in sequence from left to right and from top to bottom. (b) Trajectory indicating the motion of the tip of the spiral on the 2-D lattice. The two arrows indicate the locations of the spiral when it emerges and disappears, respectively The thick segment corresponds to the sequence shown in (a). The horizontal bars in the lowest, left-most panel of (a), and in (b) indicate the length corresponding to 10 cells, which is of the order of ∼ 1 − 2mm.