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OVCAR-3 Spheroid-Derived Cells Display Distinct Metabolic Profiles

Fig 1

Principal components analysis easily distinguishes between the metabolic profiles of OCCs and OCSCs.

Red points are OVCAR-3 cells, and green points are ovarian cancer stem cells at six different time points with three biological replicates at each time point. Principal component (PC) axes include the percentage of variation captured by each axis. A) PC 1 captures the cell type separation for the unknown and annotated analytes, with PC 2 capturing some time point separation. B) Including only the profiles of annotated, identified metabolites shows complete cell type separation in PC 1 and some time point separation in PC 2.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0118262.g001