The Notch Signaling Regulates CD105 Expression, Osteogenic Differentiation and Immunomodulation of Human Umbilical Cord Mesenchymal Stem Cells
Fig 2
The GSI-I treatment reduces expression of positive MSC surface markers.
Representative histogram from a flow cytometry assay shows that, while over 95% untreated hUC-MSCs are positive for CD73, CD90 and CD105 (A), the treatment significantly reduces the positivity for each surface marker with the most significance seen for CD105 reduction. The * indicates the statistical significance with p<0.05 (B).