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A Novel Three-Filament Model of Force Generation in Eccentric Contraction of Skeletal Muscles

Fig 7

Illustration of active shortening of a sarcomere based on the three filament model.

a, The sarcomere is passively stretched to a length of 2.6μm, activated and b, shortened to 2.4μm. The resulting force is compared to the isometric force at 2.4μm, where the sarcomere is activated at a length of 2.4μm and the elongation of its free spring length is higher, whether titin is attached to actin d or not c.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0117634.g007