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Relationship of Ocular Microcirculation, Measured by Laser Speckle Flowgraphy, and Silent Brain Infarction in Primary Aldosteronism

Fig 2

Representative cases with and without silent brain infarction.

Above: 63-year-old man without silent brain infarction (SBI). Below: 61-year-old man with SBI. Left: magnetic resonance images; middle: laser speckle flowgraphy (LSFG) color maps; right: LSFG-measured mean blur rate (MBR) waveform. The arrows in the MRI images for the SBI case show regions of clearly visible SBI. The ellipse indicates the optic nerve head (ONH) margin. The LSFG software automatically divided the overall ONH into large vessel and capillary areas. The MBR waveform for the SBI case show that the peak of the waveform is steeper and has a more clearly defined peak than the non-SBI case, which may reflect the effect of age-related vascular changes on the MBR waveform. Furthermore, the values for BOT are 56.5 and 41.6 arbitrary units in the SBI and non-SBI cases, respectively.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0117452.g002