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Genistein Improves 3-NPA-Induced Memory Impairment in Ovariectomized Rats: Impact of Its Antioxidant, Anti-Inflammatory and Acetylcholinesterase Modulatory Properties

Fig 3

H & E staining of the cortices of rats belonging to the sham group (A), control group (B), 3-NPA-treated group (C), 17β-estradiol- and 3-NPA-treated group (D), genistein (5 mg/kg)- and 3-NPA-treated group (E), genistein (10 mg/kg)- and 3-NPA-treated group (F), genistein (20 mg/kg)- and 3-NPA-treated group (G) and genistein alone-treated group (H): A, B, D and H showed no histological alterations, C showed severe hemorrhage (h), E showed focal gliosis (g) F showed focal gliosis (g) and G showed congested blood vessel (C).

Fig 3

doi: https://doi.org/10.1371/journal.pone.0117223.g003