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Transcriptional Attenuation Controls Macrolide Inducible Efflux and Resistance in Streptococcus pneumoniae and in Other Gram-Positive Bacteria Containing mef/mel(msr(D)) Elements

Fig 7

Visualization of mef(E) attenuator by RNA-Seq.

Whole transcriptome analysis by RNA-Seq of mRNA from the wild type strain GA17457, non- induced or exposed to spiramycin, the antimicrobial peptide, LL-37, or erythromycin. The number of sequence reads correlated to the mef(E)/mel transcript is shown on the graph. Dashed lines below each sample indicate transcripts predicted by Integrated Genome Viewer (IGV). The mef(E) and mel open reading frames are shown below.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0116254.g007