Fever-Range Hyperthermia vs. Hypothermia Effect on Cancer Cell Viability, Proliferation and HSP90 Expression
Figure 2
Confocal immunofluorescent microscopy images and automated quantification of ki67 proliferation marker in various cell lines.
2a: changes of Ki67 proliferation index class after 3-day exposure of cells to hypothermia (34°C) or hyperthermia (40°C) compared to normothermia (37°C). 2b: Representative confocal microcopy images showing nuclear Ki67 immunostaining changing intensity after exposure to hyperthermia (40°C).