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Active Site Loop Conformation Regulates Promiscuous Activity in a Lactonase from Geobacillus kaustophilus HTA426

Fig 2

Structures of the substrates used in this study.

(a) γ-hexyl-γ-butyrolactone; (b) δ-valerolactone; (c) δ-nonalactone; (d) δ-decanolactone; (e) ε-caprolactone; (f) p-nitrophenyl caprylate; (g) ethyl-paraoxon; (h) methyl-paraoxon; (i) ethyl-parathion; (j) methyl-parathion; (k) diazinon; (l) chlorpyrifos.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0115130.g002