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Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage

Figure 9

Accumulation of collagen in livers of Plvap-deficient mice.

By TEM of a Plvap-deficient animal at three weeks of age, bundles of collagen fibrils with the typical 67 nm periodicity are seen in Disse's space (arrows). No fibrillar extracellular matrix is present in Disse's space of the wild-type littermate. Lower panels show higher magnification.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0115005.g009