A Single Chain Variant of Factor VIII Fc Fusion Protein Retains Normal In Vivo Efficacy but Exhibits Altered In Vitro Activity
Figure 3
Activity within FXa generation assays.
(A) Affinity of FIXa to different FVIII molecules on synthetic phospholipids surface (B) FXa generation rates for Xase Complexes formed with different FVIII molecules. A representative curve is shown. All results are listed in Table 2.