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Efficient Immuno-Modulation of TH1/TH2 Biomarkers in 2,4-Dinitrofluorobenzene-Induced Atopic Dermatitis: Nanocarrier-Mediated Transcutaneous Co-Delivery of Anti-Inflammatory and Antioxidant Drugs

Figure 8

Histological stabilization of NP-based formulation.

Histological photomicrographs of AD-like skin lesions of NC/Nga mice treated with NP-based formulations compared to normal/baseline mice and treatment groups. The wavy fibers, which were stained black with VVG, represent elastic fibers. Photomicrographs were imaged under ×400-µm magnification. AD, atopic dermatitis; NPs, nanoparticles; VVG, Verhoeff-Van Giesen.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0113143.g008