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A Physiologically-Motivated Compartment-Based Model of the Effect of Inhaled Hypertonic Saline on Mucociliary Clearance and Liquid Transport in Cystic Fibrosis

Figure 5

Estimated Tc-SC retention trajectories for three patient subgroups.

Non-CF (red with dashed line), CF IS (green with dotted dashed line), CF HS (blue with line). Shaded envelope characterizes 95% confidence interval (CI) of retention prediction by the model. Pediatric CF subjects not shown due to overlap with adult CF.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0111972.g005