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Advanced Glycation End-Products Reduce Collagen Molecular Sliding to Affect Collagen Fibril Damage Mechanisms but Not Stiffness

Figure 6

Row A) Averaged (±1 SD) tissue stress–time relations from consecutive relaxation increments of size = 0.6% L0: A1) Control samples (n = 10).

A2) 6 h MGO group (n = 10). A3) The corresponding total stress decay. Row B) Collagen fibril relaxation defined as relative length change of the D-period during relaxation steps: B1) Controls B2) 6 h MGO. B3) The corresponding total change in fibril length.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0110948.g006