P2X7 Receptor Modulates Inflammatory and Functional Pulmonary Changes Induced by Silica
Figure 1
Pulmonary mechanics in wild-type (WT) and P2X7 receptor knockout (KO) mice 14 d after silica particles instillation.
A, lung static elastance (Est); B, viscoelastic component of elastance (ΔE); C - E, resistive (ΔP1), viscoelastic/inhomogeneous (ΔP2), and total lung pressures (ΔPtot), respectively in wild-type (WT) and P2X7 receptor knockout (KO) animals. Values represent mean + SEM of 6–9 animals/group (10 determinations per animal). *p <0.05 and **p <0.001 in relation to the respective control (CTRL).