Proximal Tubule Epithelial Cell Specific Ablation of the Spermidine/Spermine N1-Acetyltransferase Gene Reduces the Severity of Renal Ischemia/Reperfusion Injury
Figure 4
Measurement of polyamine levels in the kidneys of wt and PT-SSAT-Cko mice subjected to sham surgery or renal I/R injury.
Kidney polyamine contents of wt and PT-SSAT-Cko mice were measured by HPLC. a) Kidney Put, Spd and Spm levels were determined at 24 hours post-sham or I/R surgery in wt and PT-SSAT-Cko animals. b) Acetyl-N1-spermine levels in the kidneys of sham operated and injured wt and PT-SSAT-Cko mice were compared.