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Computational Modeling Reveals that a Combination of Chemotaxis and Differential Adhesion Leads to Robust Cell Sorting during Tissue Patterning

Figure 3

Speed of misspecified cells decreases with magnitude of differential adhesion,

. (a) The cell grid as time progresses (top to bottom). (b) Bar graphs showing the speeds of correctly specified (blue) and incorrectly specified cells (red) for different values of j. (c) Bar graph of the merging time for different values of . (Inset) Cell grid showing the initial configuration of the cells. The average time taken for the centroid of the misspecified to cross the boundary (dotted line in orange) is measured for 100 runs. Error bars show the standard errors.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0109286.g003