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Assessing T Cell Clonal Size Distribution: A Non-Parametric Approach

Figure 3

Clonal statistics for an autoimmune patient.

Complementary cumulative clonal frequency distributions (CDF) for an autoimmune patient [13]–[15] in double log scale: right before the treatment (blue), 10 months after (red), and 25 months after (green). Shaded areas indicate CI95 intervals for clonal frequencies. Dashed lines show power law fits , α = −2.07, α = −0.88 and α = −0.99, respectively. Least square fits performed over the interval for the time point before treatments and for the time points after.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0108658.g003