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Maternal Methylenetetrahydrofolate Reductase C677T Polymorphism and Down Syndrome Risk: A Meta-Analysis from 34 Studies

Figure 3

Forest plots (Random effect) showed significant association between MTHFR C677T polymorphism and risk of Down syndrome.

Results of individual and summary OR estimates and 95% CI of each study were shown using homozygote model (TT versus CC).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0108552.g003