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Activated Human Mast Cells Induce LOX-1-Specific Scavenger Receptor Expression in Human Monocyte-Derived Macrophages

Figure 4

Effect of histamine H1 and H2 receptor antagonists on histamine-induced macrophage LOX-1 mRNA expression.

Monocyte-derived macrophages were incubated in the presence of 10 µM histamine and the indicated concentrations of the histamine H1 and H2 receptor antagonists (pyrilamine and ranitidine, respectively) for 4 h and analyzed for LOX-1 mRNA expression. The results are presented as means ± SEM (n = 3 donors). All statistical comparisons were non-significant.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0108352.g004