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Overexpression of Extracellular Superoxide Dismutase Protects against Brain Injury Induced by Chronic Hypoxia

Figure 1

SOD activity ratio in adult mouse brain groups (WT and KI), after exposure to hypoxia (10% for 10 days) in comparison with the RA control groups (WT and KI).

Data are mean of 10 animals per group ± SEM. *P<0.05 versus the KI hypoxia and WT hypoxia groups (Fig. 1A). Quantitative Western blot for SDO1, SOD2 & hSDO3 (presented as a ratio for B-Actin), in adult mouse brain groups (WT and KI) after exposure to hypoxia (10% for 10 days) in comparison with the RA control groups (WT and KI). Data are mean of 5± SEM animals per group. *P<0.05 HI-KI vs. RA groups and WT hypoxia groups; and H-WT vs. RA groups (Fig. 1B).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0108168.g001