A Role for Smoothened during Murine Lens and Cornea Development
Figure 7
Expression of Hes 1 in LeSmox lenses.
Frozen sections stained with Hoechst dye (A, D), Hes1 antibody (B, E) and respective merged images (C, F) from Wt (A–C) and LeSmox (D–F) lenses at E16.5. A–C. In the wild-type lenses, nuclear reactivity for Hes1 was detected strongly in epithelial nuclei (arrowheds). D–F. Reactivity for Hes1 was mainly cytoplasmic in the LeSmox lenses with only occasional nuclei at the equator showing intense Hes1 reactivity. Scale bar. 100 µm.