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New Insights into the Relationship between mIGF-1-Induced Hypertrophy and Ca2+ Handling in Differentiated Satellite Cells

Figure 7

Quantification of the oxidative status and fluidity of the cell membrane lipids.

(a) Malondialdehyde levels were determined in the sarcolemma and sarcoplasmic reticulum membrane fractions from skeletal muscle biopsies of the wild-type (WT) and MLC/mIGF-1 transgenic (TG) mice. (b) Membrane fluidity of WT and TG satellite cells, measured at 0, 3 and 7 days in differentiation medium, and expressed as the ratio of fluorescence intensities at 470 and 400 nm emission wavelength (excimer/monomer). Data are means ±SEM of three independent experiments. * p<0.05, ** p<0.01 versus wild-type.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0107753.g007