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Impact of Age-Dependent Adventitia Inflammation on Structural Alteration of Abdominal Aorta in Hyperlipidemic Mice

Figure 6

Localization of IL-6 and RANTES in the abdominal aorta of 52-week old apo E−/− mice.

Representative immunostainings for IL-6 (A) and RANTES (D) in the abdominal aorta of 52-week-old apo E−/− mice. Square areas were magnified to verify the co-localization of IL-6- (B) and F4/80-positive macrophages (C) or the co-localization of RANTES- (E) and CD3-positive T-lymphocytes (F) in serial sections. Scale bar, 100 µm (A–D) and 20 µm (E, F).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0105739.g006