Hyperglycemia Promotes K-Ras-Induced Lung Tumorigenesis through BASCs Amplification
Figure 4
Assessment of tumor development and progression of lung tumors in STZ-K-RasV12 mice compared to untreated-K-RasV12 ones.
A. Average number of tumors that developed per mouse in STZ-K-RasV12 (black bar) compared to untreated-K-RasV12 (white bar) mice. B. Average tumor size (mm2) in STZ-K-RasV12 (black bar) and in untreated-K-RasV12 mice (white bar). C. Expression of neoplastic tissue with the tumor burden index which considers average number of tumors per mice and average size. Data are presented as mean ± SEM, *p<0.05 (Student's t-test).