Pyrrolobenzodiazepines (PBDs) Do Not Bind to DNA G-Quadruplexes
Table 2
FRET-based DNA thermal denaturation assay results (ΔTm values) for the interaction of the PBD monomers (1–5) and dimers (6–8) (Figure 1) with eight different G-quadruplex-forming DNA sequences and a duplex DNA control (Table 1).