Role of the Vasohibin Family in the Regulation of Fetoplacental Vascularization and Syncytiotrophoblast Formation
Figure 7
The overexpression of VASH2 augmented the fusion of BeWo cells.
A: BeWo cells were infected with adenovirus vectors. Expression of human VASH2 was quantified by qRT-PCR (N = 3). B: Cell fusion was observed as described in Materials and Methods. Bar = 100 µm. Arrowheads indicate a fused cell with multiple nuclei. Cell fusion was quantified as described in Materials and Methods (N = 3, 5 fields each). #<P0.05. C: Expression of Gcm-1 was quantified by qRT-PCR (N = 3). D: Expression of Syn-1 was quantified by qRT-PCR (N = 3). E: Expression of Syn-2 was quantified by qRT-PCR (N = 3). NS; not significant.