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A Novel Compound NSC745885 Exerts an Anti-Tumor Effect on Tongue Cancer SAS Cells In Vitro and In Vivo

Figure 2

NSC745885 induces early apoptosis in SAS cells.

SAS cells were treated with (A to E) indicated doses of NSC745885 for 24 hours. Harvested cells were stained with FITC-conjugated annexin V and analyzed by flow cytometry. (F) The percentages of annexin V positive cells under NSC745885 treatment were compared with vehicle controls (0 µM) (n = 3; **, P<0.01; ***, P<0.001; ns., non-significant).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0104703.g002