Evaluation of Retinoids for Induction of the Redundant Gene ABCD2 as an Alternative Treatment Option in X-Linked Adrenoleukodystrophy
Figure 3
ABCD2 mRNA is not induced in monocytes or lymphocytes of acne patients treated with 13CRA.
ABCD1, ABCD2, ABCD3 and HPRT mRNA levels were measured by qRT-PCR in (A) monocytes (CD14+) and (B) B cells (CD19+) of healthy controls and acne patients before and after oral treatment with 13CRA for a period of about 3 months. HPRT was used for normalization of the absolute mRNA copy numbers. Values represent means ± SEM; qRT-PCR analyses were performed in technical duplicates. The number of individuals (n) is indicated in the inserts.