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Expression Profiling of RNA Transcripts during Neuronal Maturation and Ischemic Injury

Figure 3

Differentially expressed RNA transcriptome associated with (A) cell adhesion molecules regulation, (B) proliferation and differentiation pathways, (C) neurotrophin signalling pathway, (D) differentially expressed Ikbkb and its associated ncRNAs as determined by microarray (pooled RNA from 4 separate experiments for each time point).

mRNA expression of the gene is indicated followed by the expression of the associated lncRNA (S: sense overlap; AS: antisense overlap; B: bidirectional). Differentially expressed miRNAs that are predicted to target the gene (TargetScan and microRNA.org) are indicated. Validated miRNAs are underlined. Expression is indicated in SLR relative to Day 2. Red, indicates upregulation and green, downregulation.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0103525.g003