Hypoxia-Inducible Factor 2 Alpha Is Essential for Hepatic Outgrowth and Functions via the Regulation of leg1 Transcription in the Zebrafish Embryo
Figure 12
The regulation of hepatic outgrowth by hif2-alpha in zebrafish embryos is not through the FGF, HGF, or Wnt pathways.
Gene expression of fgfr1, fgfr2, fgfr3, fgfr4, met, and epcam was examined in wild-type embryos and compared with hif2-alpha ATG-MO-injected embryos at 3–5 dpf by qPCR. Expression was normalized to β-actin.