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System Vaccinology for the Evaluation of Influenza Vaccine Safety by Multiplex Gene Detection of Novel Biomarkers in a Preclinical Study and Batch Release Test

Figure 5

Evaluation of seasonal influenza vaccine with QGP and cluster analysis.

A) Relative gene expression in HAv-treated rat lungs to Gapdh is indicated in the bar graph. B) Hierarchical clustering analysis with biomarkers could predict differences in HAv manufacturers as B is located in a separate cluster from other HAvs.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0101835.g005