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Chronopharmacology and Mechanism of Antitumor Effect of Erlotinib in Lewis Tumor-Bearing Mice

Figure 5

Influence of dosing times on P-AKT and AKT protein expression (A) or relative P-AKT and AKT protein expression (B and C) in tumor masses after erlotinib (60 mg/kg) administration.

Each value is the mean with SD of six mice. *P<0.05 when compared with the model group.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0101720.g005