Transdermal Delivery of Insulin by Amidated Pectin Hydrogel Matrix Patch in Streptozotocin-Induced Diabetic Rats: Effects on Some Selected Metabolic Parameters
Figure 5
Comparison of the effects on blood glucose of STZ-induced diabetic rats treated with transdermal PI hydrogel matrix patches on the skin and diabetic rats treated with sc insulin with untreated animals.
Animals treated with drug-free pectin and subcutaneous insulin (175 µg/kg) acted as negative and positive controls, respectively. Values are presented as means, and vertical bars indicate SEM of means (n = 6 in each group). ★p<0.05 by comparison with control animals.