Ablation of Coactivator Med1 Switches the Cell Fate of Dental Epithelia to That Generating Hair
Figure 7
Hair differentiation was induced adjacent to the blood vessels in which calcium is supplied.
(A) Hair keratin Krt71 was detected in the papillary layer adjacent to the blood vessels (right panel). Enlarged images are shown in the middle panel (Krt71 green, Notch1 red, DAPI blue). Yellow dotted circles and white arrows show the blood vessels in which erythrocytes are detected (insert). Sox2 was expressed in basal cells in the papillary layer (left panel, Sox2 green, Notch1 red, DAPI blue).