Expression and Functional Characterization of NOD2 in Decidual Stromal Cells Isolated during the First Trimester of Pregnancy
Figure 3
Effect of MDP and LPS on cytokine production by first trimester normal DSCs.
The DSCs were treated with either control medium (0 µg/ml), MDP (0.1 µg/ml, 1 µg/ml, 10 µg/ml), LPS (0.1 µg/ml, 1 µg/ml, 10 µg/ml) for 72 hrs. Cell-free supernatants were collected and assayed for cytokine concentrations. The bar charts for (A) IL-1β, (B) TNF-α, (C) IL-12, (D) MCP-1 alpha (diluted by 5 times), show significant changes in cytokine levels compared to the control (*P<0.05; **P<0.01). Data were from one representative of four independent experiments.