NGF and TERT Co-Transfected BMSCs Improve the Restoration of Cognitive Impairment in Vascular Dementia Rats
Figure 5
Protein expression analysis by western blotting.
After normalisation to actin, protein levels of NGF, TrkA, and SYN in the VaD group were significantly lower than those in the control group. The untransfected and NGF-TERT co-transfected BMSC transplanted VaD groups had significantly higher levels of these proteins than the VaD group. Additionally, rats treated with NGF-TERT co-transfected BMSCs had significantly higher levels of NGF, TrkA, and SYN than rats treated with untransfected BMSCs (*P<0.05, n = 12).