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Quantitative Characterization of Cell Behaviors through Cell Cycle Progression via Automated Cell Tracking

Figure 8

Calculation of mean square displacement (MSD) and determination of motion type.

(A) Schematic showing the selected pairs of data point along a trajectory with different time interval for the calculation of MSD. (B) MSD calculation. (C) MSD as function of time interval to determine motion type. The linear increase of the MSD with the time interval indicates the motion type of random walk. Directional motion leads to a MSD curve deflected upward, whereas depressed motion results in a MSD curve deflected downward.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0098762.g008