Neuroproteome Changes after Ischemia/Reperfusion Injury and Tissue Plasminogen Activator Administration in Rats: A Quantitative iTRAQ Proteomics Study
Figure 4
Volcano plots showing the distribution of significance and fold change of identified proteins in the (A) sham+rt-PA/sham comparison and (B) tMCAo+rt-PA/tMCAo comparison.
All proteins with 2 or more peptides were plotted with fold change on the x-axis and p-value on the y-axis. Vertical lines mark a fold change of +/−10% and the horizontal line marks p = 0.05. The 18 proteins marked in orange with text labels meet the criteria for having differential expression (>10% in either direction) and are significant (<p = 0.05).