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Role of Ferulic Acid in the Amelioration of Ionizing Radiation Induced Inflammation: A Murine Model

Figure 7

Levels of phosphorylation of IKKα/β induced by IR or IR+FA treatments.

The phosphorylation of IKKα/β was determined by western blot analysis with respect to IKKα and IKKβ expression. Lane 1: control group of mice, lane 2: FA treated mice, lane 3, 4 and 5: Mice exposed to 10 Gy γ-radiation and sacrificed after 6 hours, 24 hours, and 48 hours of radiation exposure (IR6, IR24 & IR48). Lane 6, 7 and 8: mice pretreated with FA and irradiated (FA+IR6, FA+IR24 & FA+IR48). Error bars were SEM for n = 3. p<0.05 was considered significant. Statistical comparison: * control vs. IR, #IR vs. FA+IR.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0097599.g007