The In Vivo Therapeutic Efficacy of the Oncolytic Adenovirus Delta24-RGD Is Mediated by Tumor-Specific Immunity
Figure 6
Influx of CD8+ T-cells in untreated tumor in multifocal model.
A) H&E staining of multifocal tumor model showing GL261 tumors located in both hemispheres. The right-side tumor is either treated with Delta24-RGD or PBS as a control (magnification 1,25x). B) Immunohistochemical staining for CD8+ cells. Representative image of two mice per group is shown (magnification 20x). C) Survival analysis of multifocal model (not significant, Log-Rank test).