The In Vivo Therapeutic Efficacy of the Oncolytic Adenovirus Delta24-RGD Is Mediated by Tumor-Specific Immunity
Figure 3
Delta24-RGD induces long term anti-tumor immunity.
Long term survivors (LTS, n = 4) were rechallenged with GL261 cells. A) HE staining showing tumor growth in naïve mice and the absence of tumor in the long term survivors (LTS) (magnification 1,25x (left) and 5x (right)), V is indicating the ventricle. B) Kaplan-Meier survival plot demonstrating significant survival of rechallenged mice (log-rank test p = 0.0067).