Raised Soluble P-Selectin Moderately Accelerates Atherosclerotic Plaque Progression
Figure 5
Sections of each aortic segment were analysed for lesion size, necrotic core, αSMA and collagen content in Apoe−/− HFD or SM22hDTR-ApoE−/− HFD mice, A) lesion size defined as % ORO staining, B) necrotic core defined as % unstained with Mayer’s Hematoxylin and Eosin, C) % α-SMA content, D) % collagen content. n = 6–9 mice per treatment group. Data represented as Mean (% stain) ± SEM where * represents P<0.05 as analysed by unpaired students t-test. Representative images are given for each analysis. Scale bars = 100 µm.