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Addressing RNA Integrity to Determine the Impact of Mitochondrial DNA Mutations on Brain Mitochondrial Function with Age

Figure 5

Stable Expression of Genes and Proteins with Age.

(A) Expression of mitochondrial genes was analyzed by RT-qPCR normalized to Gapdh and presented relative to 1 month old mice. (B) Expression levels of proteins were evaluated by western analyses using antibodies as specified in Experimental Procedures. The relative increase in COXI and ND6 with age is indicated. Figure shows mean with SD. **p<0.01, *p< 0.05.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0096940.g005