Contractile and Mechanical Properties of Epithelia with Perturbed Actomyosin Dynamics
Figure 3
Tissue scale recoil kinetics of wild type embryos and embryos with perturbed actomyosin dynamics.
(A–D) Power law prefactor and exponent obtained from fitting the recoil of 1st and 2nd neighbour cell vertices surrounding the wound as a function of their distance to the wound for wild type –ECadGFP- (30 embryos/165 vertices) (A), ASGal4/UASMbsN300 (24 embryos/92 vertices) (B), ASGal4/UASctMLCK (17 embryos/87 vertices) (C), and ASGal4/UASDiaCA embryos (24 embryos/128 vertices) (D). The parameters of the vertices surrounding the laser cut and 2nd neighbours are shown as disks and triangles, respectively. The decay spatial constant for power law prefactor d (E) and power law exponent α (F) are shown as mean with error bars indicating a 95% confidence interval. Stars indicate significant difference from 0 with p<0.05. The power law was fitted to each vertex individually. Details of the data fitting and the statistical testing are given in Materials and Methods.