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Antinociceptive Effect of Tetrandrine on LPS-Induced Hyperalgesia via the Inhibition of IKKβ Phosphorylation and the COX-2/PGE2 Pathway in Mice

Figure 4

Regulatory effects of TET on the NF-κB pathway in LPS-induced cultured astroglia.

(A) The expression of P65, pP65, IκBα, and pIκBα in the presence or absence of TET and LPS was assessed by western blotting, and the quantified comparisons of relative densities are shown. (B) The protein expression of IKKs in the presence or absence of TET and LPS was assessed by western blotting, and the quantified relative densities. Values are shown as M±SD, and normalized to the NS groups. *, P<0.05.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0094586.g004